Anti-RUNX2 Polyclonal Antibody-抗体-抗体-生物在线
北京索莱宝科技有限公司
Anti-RUNX2 Polyclonal Antibody

Anti-RUNX2 Polyclonal Antibody

商家询价

产品名称: Anti-RUNX2 Polyclonal Antibody

英文名称: Anti-RUNX2 Polyclonal Antibody

产品编号: K101309P

产品价格: null

产品产地: 北京

品牌商标: Solarbio

更新时间: 2025-01-15T14:04:01

使用范围: WB

北京索莱宝科技有限公司
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Anti-RUNX2 Polyclonal Antibody

品牌:solarbio | 货号:K101309P
商品货号:商品品牌:规格基本售价:选择规格
K101309P-50ulsolarbio50ul960.00元
K101309P-100ulsolarbio100ul1600.00元
 
英文名称Anti-RUNX2 Polyclonal Antibody
别名AML3;CBF-alpha-1;CBFA1;CCD;CCD1;CLCD;
OSF-2;OSF2;PEA2aA;PEBP2aA
应用WB
稀释比例WB 1:500-2000.
交叉反应Human Mouse
蛋白分子量56kDa
保存Store at -20°C. Avoid freeze / thaw cycles.
储存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法Affinity purification
亚型IgG
免疫原A synthetic peptide of human RUNX2
性状液体
Public
Immunogen
Range
A synthetic peptide of human RUNX2
Subcellular
Locations
Nucleus
Swiss ProtQ13950
克隆类型Polyclonal Antibody
背景资料Transcription factor involved in osteoblastic
differentiation and skeletal morphogenesis. Essential
for the maturation of osteoblasts and both
intramembranous and endochondral ossification. CBF
binds to the core site, 5'-PYGPYGGT-3', of a number of
enhancers and promoters, including murine leukemia
virus, polyomavirus enhancer, T-cell receptor enhancers,
osteocalcin, osteopontin, bone sialoprotein, alpha 1(I)
collagen, LCK, IL-3 and GM-CSF promoters. In
osteoblasts, supports transcription activation: synergizes
with SPEN/MINT to enhance FGFR2-mediated activation
of the osteocalcin FGF-responsive element (OCFRE) (By
similarity). Inhibits KAT6B-dependent transcriptional
activation.