Anti-RUNX2 Polyclonal Antibody
产品名称: Anti-RUNX2 Polyclonal Antibody
英文名称: Anti-RUNX2 Polyclonal Antibody
产品编号: K101309P
产品价格: null
产品产地: 北京
品牌商标: Solarbio
更新时间: 2025-01-15T14:04:01
使用范围: WB
北京索莱宝科技有限公司
- 联系人 : 索莱宝-龚思雨
- 地址 : 北京市通州区中关村科技园区通州园金桥科技产业基地景盛南四街15号85A三层
- 邮编 : 101102
- 所在区域 : 北京
- 电话 : 178****1073 点击查看
- 传真 : 点击查看
- 邮箱 : 3193328036@qq.com
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Anti-RUNX2 Polyclonal Antibody
品牌:solarbio | 货号:K101309P
英文名称 | Anti-RUNX2 Polyclonal Antibody |
---|---|
别名 | AML3;CBF-alpha-1;CBFA1;CCD;CCD1;CLCD; OSF-2;OSF2;PEA2aA;PEBP2aA |
应用 | WB |
稀释比例 | WB 1:500-2000. |
交叉反应 | Human Mouse |
蛋白分子量 | 56kDa |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 | Affinity purification |
亚型 | IgG |
免疫原 | A synthetic peptide of human RUNX2 |
性状 | 液体 |
Public Immunogen Range | A synthetic peptide of human RUNX2 |
Subcellular Locations | Nucleus |
Swiss Prot | Q13950 |
克隆类型 | Polyclonal Antibody |
背景资料 | Transcription factor involved in osteoblastic differentiation and skeletal morphogenesis. Essential for the maturation of osteoblasts and both intramembranous and endochondral ossification. CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, osteocalcin, osteopontin, bone sialoprotein, alpha 1(I) collagen, LCK, IL-3 and GM-CSF promoters. In osteoblasts, supports transcription activation: synergizes with SPEN/MINT to enhance FGFR2-mediated activation of the osteocalcin FGF-responsive element (OCFRE) (By similarity). Inhibits KAT6B-dependent transcriptional activation. |