Anti-TRAF1 Polyclonal Antibody

K001581P-50ul	Solarbio	50ul	960.00元
K001581P-100ul	Solarbio	100ul	1600.00元

英文名称	Rabbit TRAF1 Polyclonal Antibody
克隆类型2	Polyclonal Antibody
别名	EBI6;MGC:10353
应用	WB
稀释比例	WB1:500-1:2000
交叉反应	Human Mouse Rat
蛋白分子量	46kDa
Gene ID	7185
保存	Store at -20°C. Avoid freeze / thaw cycles.Stable for one year from the date of shipment.
储存液	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法	Affinity purification
亚型	IgG
免疫原	Recombinant protein of human TRAF1
性状	Lyophilized or Liquid
Swiss Prot	Q13077
克隆类型	Polyclonal Antibody
来源	Rabbit
背景资料	The protein encoded by this gene is a member of the TNF receptor (TNFR) associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from various receptors of the TNFR superfamily. This protein and TRAF2 form a heterodimeric complex, which is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB. The protein complex formed by this protein and TRAF2 also interacts with inhibitor-of-apoptosis proteins (IAPs), and thus mediates the anti-apoptotic signals from TNF receptors. The expression of this protein can be induced by Epstein-Barr virus (EBV). EBV infection membrane protein 1 (LMP1) is found to interact with this and other TRAF proteins; this interaction is thought to link LMP1-mediated B lymphocyte transformation to the signal transduction from TNFR family receptors. Three transcript variants encoding two different isoforms have been found for this gene.