Anti-SMAD2 Polyclonal Antibody-抗体-抗体-生物在线

Anti-SMAD2 Polyclonal Antibody

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产品名称： Anti-SMAD2 Polyclonal Antibody

英文名称： Anti-SMAD2 Polyclonal Antibody

产品编号： K002265P

产品价格： null

产品产地：北京

品牌商标： Solarbio

更新时间： 2025-01-13T13:42:34

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北京索莱宝科技有限公司

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Anti-SMAD2 Polyclonal Antibody

Anti-SMAD2 Polyclonal Antibody
品牌：solarbio | 货号：K002265P
商品货号： 商品品牌： 规格 基本售价： 选择规格
K002265P-50ul solarbio 50ul 960.00元
K002265P-100ul solarbio 100ul 1600.00元
英文名称 Anti-SMAD2 Polyclonal Antibody
别名 JV18;JV18-1;MADH2;MADR2;hMAD-2;hSMAD2
应用 WB IHC IF
稀释比例 WB 1:500-2000. IHC 1:50-100. IF 1:50-200.
交叉反应 Human Mouse Rat
蛋白分子量 52kDa
Gene ID 4087
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 A synthetic peptide of human SMAD2
性状 液体
Public Immunogen Range A synthetic peptide of human SMAD2
Subcellular Locations Cytoplasm Nucleus
Swiss Prot Q15796
克隆类型 Polyclonal Antibody
背景资料 The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signal of the transforming growth factor (TGF)-beta, and thus regulates multiple cellular processes, such as cell proliferation, apoptosis, and differentiation. This protein is recruited to the TGF-beta receptors through its interaction with the SMAD anchor for receptor activation (SARA) protein. In response to TGF-beta signal, this protein is phosphorylated by the TGF-beta receptors. The phosphorylation induces the dissociation of this protein with SARA and the association with the family member SMAD4. The association with SMAD4 is important for the translocation of this protein into the nucleus, where it binds to target promoters and forms a transcription repressor complex with other cofactors. This protein can also be phosphorylated by activin type 1 receptor kinase, and mediates the signal from the activin. Alternatively spliced transcript variants have been observed for this gene.

商品货号：	商品品牌：	规格	基本售价：	选择规格
K002265P-50ul	solarbio	50ul	960.00元
K002265P-100ul	solarbio	100ul	1600.00元

英文名称	Anti-SMAD2 Polyclonal Antibody
别名	JV18;JV18-1;MADH2;MADR2;hMAD-2;hSMAD2
应用	WB IHC IF
稀释比例	WB 1:500-2000. IHC 1:50-100. IF 1:50-200.
交叉反应	Human Mouse Rat
蛋白分子量	52kDa
Gene ID	4087
保存	Store at -20°C. Avoid freeze / thaw cycles.
储存液	Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法	Affinity purification
亚型	IgG
免疫原	A synthetic peptide of human SMAD2
性状	液体
Public Immunogen Range	A synthetic peptide of human SMAD2
Subcellular Locations	Cytoplasm Nucleus
Swiss Prot	Q15796
克隆类型	Polyclonal Antibody
背景资料	The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signal of the transforming growth factor (TGF)-beta, and thus regulates multiple cellular processes, such as cell proliferation, apoptosis, and differentiation. This protein is recruited to the TGF-beta receptors through its interaction with the SMAD anchor for receptor activation (SARA) protein. In response to TGF-beta signal, this protein is phosphorylated by the TGF-beta receptors. The phosphorylation induces the dissociation of this protein with SARA and the association with the family member SMAD4. The association with SMAD4 is important for the translocation of this protein into the nucleus, where it binds to target promoters and forms a transcription repressor complex with other cofactors. This protein can also be phosphorylated by activin type 1 receptor kinase, and mediates the signal from the activin. Alternatively spliced transcript variants have been observed for this gene.