Anti-EIF4EBP1 Polyclonal Antibody
产品名称: Anti-EIF4EBP1 Polyclonal Antibody
英文名称: Anti-EIF4EBP1 Polyclonal Antibody
产品编号: K002576P
产品价格: null
产品产地: 北京
品牌商标: Solarbio
更新时间: 2025-01-14T09:56:36
使用范围:
北京索莱宝科技有限公司
- 联系人 : 索莱宝-龚思雨
- 地址 : 北京市通州区中关村科技园区通州园金桥科技产业基地景盛南四街15号85A三层
- 邮编 : 101102
- 所在区域 : 北京
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- 邮箱 : 3193328036@qq.com
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Anti-EIF4EBP1 Polyclonal Antibody
Anti-EIF4EBP1 Polyclonal Antibody
品牌:solarbio | 货号:K002576P
英文名称 | Anti-EIF4EBP1 Polyclonal Antibody |
---|---|
别名 | 4E-BP1;4EBP1;BP-1;PHAS-I |
应用 | WB IF |
稀释比例 | WB 1:500-1000. IF 1:50-200. |
交叉反应 | Human Mouse Rat |
蛋白分子量 | 13kDa |
Gene ID | 1978 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 | Affinity purification |
亚型 | IgG |
免疫原 | A synthetic peptide of human EIF4EBP1 |
性状 | 液体 |
Public Immunogen Range | A synthetic peptide of human EIF4EBP1 |
Subcellular Locations | Cytosol |
Swiss Prot | Q13541 |
克隆类型 | Polyclonal Antibody |
背景资料 | This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation. |