TPMT Polyclonal Antibody
产品名称: TPMT Polyclonal Antibody
英文名称: TPMT Polyclonal Antibody
产品编号: K001870P
产品价格: null
产品产地: 北京市通州区马驹桥联
品牌商标: solarbio
更新时间: 2025-01-14T09:56:36
使用范围:
北京索莱宝科技有限公司
- 联系人 : 索莱宝-龚思雨
- 地址 : 北京市通州区中关村科技园区通州园金桥科技产业基地景盛南四街15号85A三层
- 邮编 : 101102
- 所在区域 : 北京
- 电话 : 178****1073 点击查看
- 传真 : 点击查看
- 邮箱 : 3193328036@qq.com
- 二维码 : 点击查看
Anti-TPMT Polyclonal Antibody
品牌:solarbio | 货号:K001870P
英文名称 | Anti-TPMT Polyclonal Antibody |
---|---|
别名 | TPMTD |
应用 | WB IHC IF |
稀释比例 | WB 1:500-2000. IHC 1:50-200. IF 1:10-100. |
交叉反应 | Human Mouse |
蛋白分子量 | 28kDa |
Gene ID | 7172 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 | Affinity purification |
亚型 | IgG |
免疫原 | Recombinant protein of human TPMT |
性状 | 液体 |
Public Immunogen Range | Recombinant protein of human TPMT |
Subcellular Locations | Cytoplasm |
Swiss Prot | P51580 |
克隆类型 | Polyclonal Antibody |
背景资料 | This gene encodes the enzyme that metabolizes thiopurine drugs via S-adenosyl-L-methionine as the S-methyl donor and S-adenosyl-L-homocysteine as a byproduct. Thiopurine drugs such as 6-mercaptopurine are used as chemotherapeutic agents. Genetic polymorphisms that affect this enzymatic activity are correlated with variations in sensitivity and toxicity to such drugs within individuals, causing thiopurine S-methyltransferase deficiency. Related pseudogenes have been identified on chromosomes 3, 18 and X. |