Anti-PDGFB Polyclonal Antibody

商品货号：	商品品牌：	规格	基本售价：	选择规格
K002386P-50ul	solarbio	50ul	960.00元
K002386P-100ul	solarbio	100ul	1600.00元

英文名称	Anti-PDGFB Polyclonal Antibody
别名	IBGC5;PDGF-2;PDGF2;SIS;SSV;c-sis
应用	WB IHC
稀释比例	WB 1:500-2000. IHC 1:50-200.
交叉反应	Human Mouse Rat
蛋白分子量	27kDa
Gene ID	5155
保存	Store at -20°C. Avoid freeze / thaw cycles.
储存液	Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法	Affinity purification
亚型	IgG
免疫原	Recombinant protein of human PDGFB
性状	液体
Public Immunogen Range	Recombinant protein of human PDGFB
Subcellular Locations	Secreted
Swiss Prot	P01127
克隆类型	Polyclonal Antibody
背景资料	This gene encodes a member of the protein family comprised of both platelet-derived growth factors (PDGF) and vascular endothelial growth factors (VEGF). The encoded preproprotein is proteolytically processed to generate platelet-derived growth factor subunit B, which can homodimerize, or alternatively, heterodimerize with the related platelet-derived growth factor subunit A. These proteins bind and activate PDGF receptor tyrosine kinases, which play a role in a wide range of developmental processes. Mutations in this gene are associated with meningioma. Reciprocal translocations between chromosomes 22 and 17, at sites where this gene and that for collagen type 1, alpha 1 are located, are associated with dermatofibrosarcoma protuberans, a rare skin tumor. Alternative splicing results in multiple transcript variants.