CREBL2 MaxPab mouse polyclonal antibody (B01)
产品名称： CREBL2 MaxPab mouse polyclonal antibody (B01)
英文名称： CREBL2 MaxPab mouse polyclonal antibody (B01)
产品编号： H00001389-B01
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse polyclonal antibody raised against a full-length human CREBL2 protein.
- Immunogen:
- CREBL2 (NP_001301.1, 1 a.a. ~ 120 a.a) full-length human protein.
- Sequence:
- MDDSKVVGGKVKKPGKRGRKPAKIDLKAKLERSRQSARECRARKKLRYQYLEELVSSRERAICALREELEMYKQWCMAMDQGKIPSEIKALLTGEEQNKSQQNSSRHTKAGKTDANSNSW
- Host:
- Mouse
- Reactivity:
- Human
- Storage Buffer:
- No additive
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody reactive against mammalian transfected lysate.
- Note:
- For IHC and IF applications, antibody purification with Protein A will be needed prior to use.
- MSDS:
Download
- Applications
- Western Blot (Transfected lysate)
- Western Blot analysis of CREBL2 expression in transfected 293T cell line (H00001389-T01) by CREBL2 MaxPab polyclonal antibody.
Lane 1: CREBL2 transfected lysate(13.2 KDa).
Lane 2: Non-transfected lysate. - Protocol Download
- Entrez GeneID:
- 1389
- GeneBank Accession#:
- NM_001310.2
- Protein Accession#:
- NP_001301.1
- Gene Name:
- CREBL2
- Gene Alias:
- MGC117311,MGC138362
- Gene Description:
- cAMP responsive element binding protein-like 2
- Omim ID:
- 603476
- Gene Ontology:
- Hyperlink
- Gene Summary:
- cAMP response element (CRE)-binding protein-like-2 (CREBL2) was identified in a search to find genes in a commonly deleted region on chromosome 12p13 flanked by ETV6 and CDKN1B genes, frequently associated with hematopoietic malignancies, as well as breast, non-small-cell lung and ovarian cancers. CREBL2 shares a 41% identity with CRE-binding protein (CREB) over a 48-base long region which encodes the bZip domain of CREB. The bZip domain consists of about 30 amino acids rich in basic residues involved in DNA binding, followed by a leucine zipper motif involved in protein dimerization. This suggests that CREBL2 encodes a protein with DNA binding capabilities. The occurance of CREBL2 deletion in malignancy suggests that CREBL2 may act as a tumor suppressor gene. [provided by RefSeq
- Other Designations:
- -